3DS:
* The worldwide release of the 3DS system.
* An announcement that Final Fantasy V and Final Fantasy VI remakes are being developed for the system.
* Information (via screenshots, video, etc.) that suggests the folks at Nintendo have (wisely) decided against making the characters in Animal Crossing 3DS more realistically proportioned.
DS:
* A European and North American release of Professor Layton and the Specter's Flute (aka Professor Layton and the Flute of Malevolent Destiny).
* The European release of Inazuma Eleven.
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PSP:
* A North American release of Final Fantasy IV Complete Collection.
* A North American UMD release of ClaDun 2--with the first ClaDun, previously a PSN-only title in the States, included as a bonus (à la What Did I Do To Deserve This, My Lord!? 2).
* The release of the PSP Minis version of Pac-Man: Championship Edition.
PS3:
* A price drop of the basic PS3 system to $199.
Xbox 360:
* A price drop of the Xbox 360 "Arcade" system to $149.
Wii:
* The release of the first screenshots of Dragon Quest X.
* The Japanese release of Rhythm Heaven Wii.
* A North American release of Xenoblade. (Hey, a guy can dream.)
What games, systems, etc., are you looking forward to in 2011?